Egypt has been rocked by further clashes between supporters of the Muslim Brotherhood-led government of Mohamed Morsi and opposition activists.

Four people were reported to have been killed and more than 300 people injured in Cairo during the violence which centred on the district around the presidential palace. The interior ministry said at least 32 people had been arrested and three police vehicles destroyed.

In the city of Ismailia, east of Cairo, protesters set alight the headquarters of Morsi's Freedom and Justice Party which is dominated by the Brotherhood.

Mohamed ElBaradei, a leading opposition advocate of reform, accused Morsi's supporters of a "vicious and deliberate" attack against peaceful demonstrators.

"We hold President Morsi and his government completely responsible for the violence that is happening in Egypt today," he said.

"A regime that is not able to protect its people and is siding with his own sect, [and] thugs is a regime that lost its legitimacy and is leading Egypt into violence and bloodshed."

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